Diffuse lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: A case report
Identifieur interne : 006038 ( Main/Exploration ); précédent : 006037; suivant : 006039Diffuse lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: A case report
Auteurs : V. M. S. De Bruin [Royaume-Uni] ; Andrew Lees (neurologue) [Royaume-Uni] ; S. E. Daniel [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 1992.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Alzheimer Disease (diagnosis), Alzheimer Disease (pathology), Brain (pathology), Case study, Dementia (diagnosis), Dementia (pathology), Diagnosis, Differential, Eye Movements (physiology), Human, Humans, Inaugural sign, Lewy Bodies (ultrastructure), Lewy body, Lewy body disease, Male, Neurologic Examination, Parkinson Disease (diagnosis), Parkinson Disease (pathology), Parkinson Disease, Secondary (diagnosis), Parkinson Disease, Secondary (pathology), Steele‐Richardson‐Olszewski syndrome, Supranuclear Palsy, Progressive (diagnosis), Supranuclear Palsy, Progressive (pathology), Supranuclear ophthalmoplegia, Symptomatology.
- MESH :
- diagnosis : Alzheimer Disease, Dementia, Parkinson Disease, Parkinson Disease, Secondary, Supranuclear Palsy, Progressive.
- pathology : Alzheimer Disease, Brain, Dementia, Parkinson Disease, Parkinson Disease, Secondary, Supranuclear Palsy, Progressive.
- physiology : Eye Movements.
- ultrastructure : Lewy Bodies.
- Aged, Diagnosis, Differential, Humans, Male, Neurologic Examination.
Abstract
A 67‐year‐old man with a family history of parkinsonism had visual complaints due to difficulty in convergence, which was followed 2 years later by development of bradykinesia and rigidity. The diagnosis of Steele Richardson‐Olszewski syndrome was made on the basis of a supranuclear gaze palsy, bradykinesia, rigidity, and poor response to levodopa. However, subsequent neuropathological examination revealed diffuse Lewy body disease with no evidence of neurofibrillary tangles involving either subcortical or brain stem structures.
Url:
DOI: 10.1002/mds.870070410
Affiliations:
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The diagnosis of Steele Richardson‐Olszewski syndrome was made on the basis of a supranuclear gaze palsy, bradykinesia, rigidity, and poor response to levodopa. However, subsequent neuropathological examination revealed diffuse Lewy body disease with no evidence of neurofibrillary tangles involving either subcortical or brain stem structures.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement><orgName><li>National Hospital for Neurology and Neurosurgery</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="De Bruin, V M S" sort="De Bruin, V M S" uniqKey="De Bruin V" first="V. M. S." last="De Bruin">V. M. S. De Bruin</name></region><name sortKey="Daniel, S E" sort="Daniel, S E" uniqKey="Daniel S" first="S. E." last="Daniel">S. E. Daniel</name><name sortKey="Lees, A J" sort="Lees, A J" uniqKey="Lees A" first="A. 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